"Secretary Clinton's big victory in New York yesterday knocks Bernie Sanders pretty much out of the race. Barring an indictment over the email situation, she will represent the Democratic Party. Donald Trump also scored big and it looks like he will get the Republican nod. Talking Points does not see a way for the GOP establishment to stop Mr. Trump, even if he doesn't have the 1,237 delegates needed to be nominated on the first ballot. So I must admit that I am stunned. The two most shocking political stories in my lifetime are the assassination of President Kennedy and the rise to political prominence of Donald J. Trump. History will record that this was an uprising, a movement of the people supporting a candidate who has absolutely no ties to the political establishment. Republican voters are so angry they don't care what Mr. Trump says about other people. They don't care if his programs are controversial. They simply want to hear his message stated in a blunt way. Trump's strategy has been brilliant in mobilizing support, but it has also put him in a position where most Americans view him unfavorably. The Real Clear Politics average has Mr. Trump's unfavorable rating at 65%, while Hillary Clinton's is at 54%. Those numbers can come down because now it's really a one-on-one race. That being said, Bernie Sanders will likely hang in because if Mrs. Clinton is indicted, he'll be in line for the nomination. I also expect Ted Cruz to compete energetically in the remaining primaries and John Kasich to at least make it through the Northeast primaries that come to a head next Tuesday. All in all, tall cotton right now for Donald Trump and Hillary Clinton. Like them or not, you have to give both credit for entering a very tough arena and coming out victorious."

The Factor welcomed Donald Trump, who analyzed his huge win. "I don't know why you're so surprised," Trump said, "I've had victories my whole life. I would say I'm not surprised because this is about jobs and the economy. My message to 'make America great again' has been a great message from the moment I announced. I love the process, I love the people, and this country has so much potential that we are not using." Trump also opined on his high negative ratings. "I was being hit from every angle, so I had to be very tough and in some cases nasty. Now it looks like we are in good shape to make it to the end and take on 'crooked Hillary.'" The Factor lauded Trump for his unprecedented political rise: "What you have accomplished has never really been done in this country. You inoculated yourself against all the negative ads and publicity by being a unique presence in the political arena."

Returning for another segment, Donald Trump turned to his prospective duel against Hillary Clinton. "I like to brand people honestly," he said, "and I branded her 'crooked Hillary' because she has a lot of problems. They are going to be very tough with me, I've read that they're doing all kinds of opposition research. There will be retaliation, as there should be, but if they treat me fairly I will treat them fairly. Bernie Sanders made a big mistake by not going after her emails, which are a big part of her life story." The Factor warned Trump that he can expect vicious attacks from Clinton surrogates: "She has some nasty pieces of work on her payroll. They will come after you by leaking stuff to left-wing websites."

Bernie Sanders is on the ropes, perhaps even down for the count if you prefer another boxing cliché, after being trounced by Hillary Clinton in New York. Fox News correspondent Ed Henry reported the latest from the Democratic race. "I spoke to Sanders campaign officials," he said, "and they're still talking like they could go on a run in Pennsylvania next week. They're also talking tough about how they can flip some of these super-delegates, but there is little evidence of that. The Sanders campaign seems to be in a bit of denial. Hillary Clinton really needs the millions of Sanders supporters who are not enthused about Hillary Clinton."

Guests: Monica Crowley & Eboni Williams
President Obama says he opposes legislation that would allow families of 9/11 attack victims to sue Saudi Arabia. He says such lawsuits could have major consequences overseas and could leave us open to retaliatory acts. Tonight we'll debate whether he made the right move.

The Factor turned Dennis Miller loose on the New York State primaries. "What can you say other than it was another huge night for John Kasich," Miller joked, "who continues to move through this election like Sherman through Georgia. On the Democratic side, 'Mrs. Doubt-liar' once again crushed that 'Berning sensation.' Bernie is learning that it's not good to have supporters who are as disorganized as adults who need other people's stuff. I think Bernie could do a beer ad as 'the least interesting man in the world,' or he could work for KFC and become Colonel Bernie Sanders. The tag line would be, 'Other people's stuff is finger-lickin' good!'"

Pollster Frank Luntz, who has been taking the pulse of the electorate, looked ahead to the general election. "I give Hillary Clinton a slight 4 - 3 advantage," he began. "Trump picks up blue collar workers in places like Michigan and Pennsylvania, but he loses Latinos, 18-29 year olds, and women under 50. You can not win as a Republican if you are losing young people by a 2 - 1 margin. On the other hand, some African Americans, who won't vote for any other Republican, may vote for Donald Trump. They like his tone, he is against 'the man,' and he is tough on Washington." Considering Trump's appeal to men and his trouble with women, Luntz predicted "the biggest gender gap we have ever had in American history."

Diane Young, Waban, WA: "Bill, your Talking Points on Monday was the best ever! I believe government handouts do not equal success in life. Keep focusing on the big lie."

Al Sheldon, Loveland, OH: "Bill, you need to stop calling Americans dumb and unwilling to work. You are way too smart to expect a positive result from a negative delivery. That's my tip of the day."

Rick Hammond, Jamestown, NY: "Did I really hear Charles Krauthammer say that FDR made the right decision in making the federal government more intrusive?"

It looks like Andrew Jackson's visage will be replaced on the $20 bill by that of Harriet Tubman, who was born a slave and became a heroic freedom fighter.