Tonight's rundown: 

• Talking Points Memo: Bill runs through why the left is upset over Elon Musk's new Twitter
• White House press secretary Karine Jean-Pierre blatantly lies, and the media gives her a pass
• Fentanyl overdose deaths skyrocket in Los Angeles.
• Bill spars with Chris Cuomo on NewsNation over drug addiction and evil
• CNN announces layoffs
• This Day in History: 1824 Presidential Election
• Final Thought: Take it easy this weekend.  Everyone needs a break after Thanksgiving